Temperature-related expression of the vacuolar aspartic proteinase (APR1) gene and β-N-acetylglucosaminidase (HEX1) gene during Candida albicans morphogenesis
نویسندگان
چکیده
منابع مشابه
Molecular cloning and expression of the Candida albicans beta-N-acetylglucosaminidase (HEX1) gene.
beta-N-Acetylglucosaminidase was purified from the spent culture medium of Candida albicans A72 grown in the presence of N-acetylglucosamine (GlcNAc). The N-terminal amino acid sequence of the protein was determined, two degenerate oligonucleotide probes were constructed, and a 3.9-kb BamHI fragment of DNA that hybridized to both probes was subcloned from a lambda EMBL4 library of C. albicans A...
متن کاملQuantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans
Background and Purpose: The frequency of opportunistic fungal infections in immunocompromised patients, especially by Candida species, has sharply increased in the last few decades. The objective of this study was to analyse the ergosterol content and gene expression profiling of clinical isolates of fluconazole resistant Candida albicans. Materials and Methods: Sixty clinical samples were ide...
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BACKGROUND Intracellular aspartic proteinase A enzyme is expressed by the APR1 gene and is one of the important factors in the development of systemic candidiasis caused by Candida albicans. OBJECTIVES The aim of this study was to evaluate the expression of the APR1 gene in C. albicans isolates obtained from patients with multiple sclerosis (MS) and from controls. PATIENTS AND METHODS The s...
متن کاملevaluation of apr1 gene expression in candida albicans strains isolated from patients with multiple sclerosis
conclusions the results suggested that apr1 gene expression in c. albicans strains isolated from ms patients may be an important factor for invasive c. albicans strains in the progression of ms disease. results there was a statistically significant difference in apr1 gene expression of c. albicans strains between ms patients (mean ± sd: 0.5208 ± 0.11518) and the control group (mean ± sd: 0.7603...
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Candida albicans has the ability to change between yeast and hyphal cells and is known to be a virulence property. Efg1gene of C.albicans is as a main transcription factor that plays pivotal roles in biofilm formation The aim of the current study is to investigate the presence of Efg1 gene in Candida albicans isolates from women with vaginal candidiasis and its impact on biofilm formation.We us...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 2006
ISSN: 0378-1097
DOI: 10.1111/j.1574-6968.1997.tb10296.x